(4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone CAS 1245646-55-2
| CAS No. | 1245646-55-2 |
| Molecular Formula | C12H8Cl2N2O2 |
| Molecular Weight | 283.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone.
(4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone (CAS 1245646-55-2) is a high-purity analytical reference standard with the molecular formula C12H8Cl2N2O2 and a molecular weight of 283.11 g/mol.
Structurally, (4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone (C12H8Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 283.11 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N2O2 |
| Molecular Weight | 283.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloropyrimidin Standards
- 2-((2,5-Dichloropyrimidin-4-yl)amino)benzamide (CAS 1042434-76-3)
- 1-(4,6-Dichloropyrimidin-2-yl)-3-phenylurea (CAS 65004-55-9)
- 2-((2,6-Dichloropyrimidin-4-yl)amino)-6-methylpyridine-3-thiol (CAS 81587-38-4)
- 4-((2,4-Dichloropyrimidin-5-yl)methyl)piperazine-2-carboxylic acid (CAS 1420786-07-7)
- 4-((2,6-Dichloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile (CAS 1225383-63-0)
- (2,6-Dichloropyrimidin-4-yl)-(4-fluorophenyl)methanone (CAS 1099597-81-5)
- Ethyl 2-(2,4-dichloropyrimidin-5-yl)-2,2-difluoroacetate (CAS 2112532-59-7)
- 2-(2,5-Dichloropyrimidin-4-ylamino)-N-methylbenzamide (CAS 761440-08-8)
Recommended Standards
- 3-(Chloromethyl)-N-(5-chloro-2-pyridinyl)-2-pyrazinecarboxamide (CAS 1122549-47-6)
- 4-[bromo(phenyl)methyl]-1,2-difluorobenzene (CAS 1248278-90-1)
- 2,4-Dichloro-N'-(furan-2-ylmethylene)benzohydrazide (CAS 107401-25-2)
- 1-(4-Iodophenyl)cyclobutanecarbonitrile (CAS 1260770-24-8)
- SR 142948A (CAS 184162-21-8)
- (S)-tert-Butyl 2-(2-cyanoacetyl)pyrrolidine-1-carboxylate (CAS 173690-69-2)
- 6-Chloro-2-dimethylamino-4-trifluoromethyl-nicotinamide (CAS 1311278-46-2)
- 1-(1-methyl-1H-pyrazol-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1153295-65-8)
- Acetaminophen Impurity 39 (CAS 93629-82-4)
- (S)-Methyl 3-methyl-2-(methylamino)butanoate (CAS 35016-37-6)
- 2-(3,4-Diphenyl-1H-pyrrol-2-yl)benzoic acid (CAS 22129-82-4)
- (6-(2,2,2-Trifluoroacetyl)pyridin-3-yl)boronic acid (CAS 1310384-03-2)
- 6-Chloro-N2,N4-bis(2,4-difluorophenyl)-1,3,5-triazine-2,4-diamine (CAS 2272-38-0)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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