Ethyl 2-bromo-5-(chlorosulfonyl)thiophene-3-carboxylate CAS 1245647-67-9
| CAS No. | 1245647-67-9 |
| Molecular Formula | C7H6BrClO4S2 |
| Molecular Weight | 333.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 2-bromo-5-(chlorosulfonyl)thiophene-3-carboxylate (CAS 1245647-67-9) is a high-purity analytical reference standard with the molecular formula C7H6BrClO4S2 and a molecular weight of 333.61 g/mol.
The molecular framework of Ethyl 2-bromo-5-(chlorosulfonyl)thiophene-3-carboxylate (C7H6BrClO4S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BrClO4S2 |
| Molecular Weight | 333.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 2 |
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