4-Chloro-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine CAS 1245649-52-8
| CAS No. | 1245649-52-8 |
| Molecular Formula | C13H8ClN3O4S |
| Molecular Weight | 337.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1245649-52-8), molecular formula C13H8ClN3O4S and molecular weight 337.74 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8ClN3O4S |
| Molecular Weight | 337.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-Chloro-4-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227266-88-7)
- 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo-[2,3-d]pyrimidine-6-carboxylic acid (CAS 1346447-16-2)
- 6-(4-Chloro-3-nitrophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1437481-63-4)
- 3-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoic acid (CAS 1227954-73-5)
- 2-(2-Chloro-6-ethoxy-4-formylphenoxy)-N-(furan-2-ylmethyl)acetamide (CAS 923776-04-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N1,N1,N3,N3-tetramethylmalonamide (CAS 338406-79-4)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetohydrazide (CAS 338979-10-5)
- 6-Chloro-3-((4-fluorophenyl)sulfonyl)quinolin-4(1H)-one (CAS 866727-77-7)
Recommended Standards
- N-(4-chloro-3-nitrophenyl)-2-((4-fluorobenzyl)amino)acetamide (CAS 882080-00-4)
- n-(3-Chloro-4-fluorophenyl)-2-(4-formyl-2-methoxyphenoxy)acetamide (CAS 553628-53-8)
- 1-(4-Chlorophenyl)-1H-pyrido[2,3-e][1,3,4]thiadiazine-3-carboxylic acid 4,4-dioxide (CAS 1774901-24-4)
- 7-Chloro-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine (CAS 477861-91-9)
- 1-Methoxy-3-(m-tolylthio)propan-2-one (CAS 1522345-55-6)
- 6-(3-Isopropoxyphenoxy)pyridin-3-ylamine (CAS 1311137-94-6)
- 3-(Thiophen-2-yl)pyrazine-2-carboxylic acid (CAS 1368962-51-9)
- Methyl 2-(piperidin-4-yloxy)acetate (CAS 721391-32-8)
- 2-((2-Aminophenyl)thio)acetohydrazide (CAS 1226022-81-6)
- 4-[(3-Iodophenyl)carbonyl]morpholine (CAS 349118-63-4)
- 1-Cyclopropyl-1H-1,2,3-triazol-4-amine (CAS 1622839-02-4)
- 2-amino-4-(trifluoromethyl)benzenethiol (CAS 19406-49-6)
- tert-Butyl 3-(1-hydroxybutan-2-ylidene)azetidine-1-carboxylate (CAS 2648904-70-3)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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