2-Fluoro-6-(m-tolyl)pyridine CAS 1245650-01-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1245650-01-4
Molecular FormulaC12H10FN
Molecular Weight187.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-6-(m-tolyl)pyridine CAS 1245650-01-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 187.21 g/mol gives 2-Fluoro-6-(m-tolyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Fluoro-6-(m-tolyl)pyridine (CAS 1245650-01-4), molecular formula C12H10FN and molecular weight 187.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Fluoro-6-(m-tolyl)pyridine (C12H10FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Fluoro-6-(m-tolyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H10FN
Molecular Weight187.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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