1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine CAS 1245772-66-0
| CAS No. | 1245772-66-0 |
| Molecular Formula | C5H7F2N3 |
| Molecular Weight | 147.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine (CAS 1245772-66-0), molecular formula C5H7F2N3 and molecular weight 147.13 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C5H7F2N3, 1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine contains a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 147.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F2N3 |
| Molecular Weight | 147.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3-methyl-1H-pyrazol-4-amine (CAS 1201935-88-7)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5-amine (CAS 1245806-69-2)
- 5-(difluoromethyl)-3-ethyl-1H-1,2,4-triazole (CAS 1247413-25-7)
- 1-(Difluoromethyl)-4-methyl-1h-pyrazol-3-amine (CAS 1340566-75-7)
- [1-(difluoromethyl)-1h-pyrazol-4-yl]methanamine (CAS 1365942-99-9)
- (5-(Difluoromethyl)-1h-pyrazol-4-yl)methanamine (CAS 1461869-02-2)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-amine (CAS 1801762-09-3)
- 3-(Difluoromethyl)-5-methyl-1H-pyrazol-4-amine (CAS 2450343-56-1)
Recommended Standards
- 2-Formyl-3-hydroxybenzonitrile (CAS 1243286-54-5)
- 2-Ethynylisonicotinic acid (CAS 1240618-14-7)
- Furo[3,2-c]pyridine-6-carbaldehyde (CAS 122534-91-2)
- 3-Ethynylisonicotinic acid (CAS 1254166-43-2)
- (R)-tert-Butyl methyl(pyrrolidin-3-yl)carbamate (CAS 392338-15-7)
- 1-Aminocyclopentanecarboxylic acidHCl (CAS 92398-48-6)
- 7-Bromo-3-methyl-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-one (CAS 2020021-56-9)
- Azelastine impurity 54 (CAS CATO-C4X-139654)
- N-(2,4-Dichlorophenyl)-4-methylbenzamide (CAS 331435-42-8)
- 2,2-bis(chloromethyl)butan-1-ol (CAS 5381-54-4)
- 5,6-Dibromo-2,3-dihydro-1H-inden-1-amine (CAS 1824088-28-9)
- 1-Chloro-4-methoxy-4-methylpentane (CAS 61599-12-0)
- 2-Chloro-6-methoxy-3-methyl-5-phenylpyridine (CAS 142330-96-9)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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