Ethyl 5-bromo-1,2-dimethyl-1H-indole-3-carboxylate CAS 1245933-91-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1245933-91-8
Molecular FormulaC13H14BrNO2
Molecular Weight296.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 5-bromo-1,2-dimethyl-1H-indole-3-carboxylate CAS 1245933-91-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Ethyl 5-bromo-1,2-dimethyl-1H-indole-3-carboxylate (CAS 1245933-91-8), molecular formula C13H14BrNO2 and molecular weight 296.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl 5-bromo-1,2-dimethyl-1H-indole-3-carboxylate (C13H14BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures Ethyl 5-bromo-1,2-dimethyl-1H-indole-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H14BrNO2
Molecular Weight296.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentBr-containing
Nitrogen Atoms1

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