Ramipril EP Impurity J CAS 1246253-05-3
| CAS No. | 1246253-05-3 |
| Molecular Formula | C23H32N2O5 |
| Molecular Weight | 416.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ramipril EP Impurity J under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Ramipril EP Impurity J (CAS 1246253-05-3, C23H32N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ramipril EP Impurity J (C23H32N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H32N2O5 |
| Molecular Weight | 416.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Ramipril Standards
- Ramipril Impurity 1 (CAS CATO-C4X-17441)
- Ramipril (CAS 87333-19-5)
- Ramipril Impurity 27 (CAS 753405-33-3)
- Ramipril EP Impurity I (CAS 129939-65-7)
- Ramipril EP Impurity N (CAS 129939-63-5)
- Ramipril EP Impurity L (CAS 1309040-96-7)
- Ramipril EP Impurity L(mixture) (CAS CATO-C4X-174412)
- Ramipril-d5 (CAS 1132661-86-9)
Recommended Standards
- Trandolapril EP Impurity A (CAS 118194-41-5)
- Methylprednisolone Acetate EP Impurity J (CAS 1048031-82-8)
- Methylprednisolone EP Impurity J (CAS 53-36-1)
- Prednisolone Impurity 61 (CAS 50718-16-6)
- Terbutaline impurity 120 (CAS CATO-C4X-1183120)
- Lercanidipine Impurity 32 (CAS 3188-13-4)
- Amlodipine Impurity 110 (CAS CATO-C4X-1095110)
- 1-(Oxan-4-ylmethyl)-3-phenyl-1H-pyrazol-5-amine (CAS 1448854-63-4)
- Phenoxymethylpenicillin Impurity 12 (CAS CATO-C4X-212612)
- (Z)-4-Methoxy-1-(4-methoxyphenyl)-1,4-dioxo-3-(pyridin-1-ium-1-yl)but-2-ene-2-thiolate (CAS 2417676-79-8)
- 2-(1-Allyl-1H-indol-2-yl)-5-methyl-1,3,4-oxadiazole (CAS 921523-65-1)
- Dimethyl 1-(2-(4-chlorophenyl)-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 1350929-63-3)
- (5-Bromopyridazin-3-yl)methanol (CAS 1894088-87-9)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com