(4-Pentafluoroethyl-5-trifluoromethyl-pyridin-2-yl)-hydrazine CAS 1246466-47-6
| CAS No. | 1246466-47-6 |
| Molecular Formula | C8H5F8N3 |
| Molecular Weight | 295.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (4-Pentafluoroethyl-5-trifluoromethyl-pyridin-2-yl)-hydrazine (C8H5F8N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(4-Pentafluoroethyl-5-trifluoromethyl-pyridin-2-yl)-hydrazine (CAS 1246466-47-6), molecular formula C8H5F8N3 and molecular weight 295.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-Pentafluoroethyl-5-trifluoromethyl-pyridin-2-yl)-hydrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F8N3 |
| Molecular Weight | 295.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Pentafluoroethyl Standards
- (4-Pentafluoroethyl-6-trifluoromethyl-pyridin-2-yl)-hydrazine (CAS 1208079-08-6)
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- 5-Methyl-7-(pentafluoroethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 676469-64-0)
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- 2-(1,1,2,2,2-PEntafluoroethyl)-2-phenylazepane (CAS 910443-00-4)
- 2-Pentafluoroethyl-3-trifluoromethyl-6-chloropyridine (CAS 1246466-64-7)
- 5-Pentafluoroethyl-6-trifluoromethyl-nicotinonitrile (CAS 1246466-62-5)
Recommended Standards
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- [(2-Chloro-4-Oxooxetan-2-Yl)Methyl]Pentafluorosulfur(VI) (CAS 70353-68-3)
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- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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