4-[(Pyridin-2-yl)methyl]piperidin-4-ol hydrochloride CAS 1246633-40-8
| CAS No. | 1246633-40-8 |
| Molecular Formula | C11H16N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(Pyridin-2-yl)methyl]piperidin-4-ol hydrochloride (CAS 1246633-40-8), molecular formula C11H16N2OHCl and molecular weight 228.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(Pyridin-2-yl)methyl]piperidin-4-ol hydrochloride (C11H16N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(Pyridin-2-yl)methyl]piperidin-4-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O HCl |
| Molecular Weight | 228.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pyridin Standards
- 3-[(E)-2-(Pyridin-3-yl)ethenyl]-1,2-dihydroquinoxalin-2-one (CAS 1000169-10-7)
- 2-(pyridin-2-ylsulfanyl)acetic acid (CAS 10002-29-6)
- 4-(Pyridin-3-yloxy)benzenesulfonic acid (CAS 1000340-09-9)
- 2-(2-Oxo-2-(pyridin-4-yl)ethylidene)thiazolidin-4-one (CAS 1000932-15-9)
- 2-[2-oxo-2-(pyridin-3-yl)ethylidene]-1,3-thiazolidin-4-one (CAS 1000932-62-6)
- N-(pyridin-3-ylmethyl)sulfamide (CAS 1000933-31-2)
- Ethyl 1-(2-pyridin-2-ylethyl)piperidine-4-carboxylate (CAS 1000941-29-6)
- 1-Methyl-4-(pyridin-2-ylmethyl)piperazine (CAS 100158-57-4)
Recommended Standards
- (Glu20)-Amyloid β-Protein (1-42) (CAS 1802086-22-1)
- 4-(4-Amino-3-nitrophenyl)phthalazin-1-ol (CAS 58370-64-2)
- 5-Bromo-2-(methylamino)benzaldehyde (CAS 1289004-26-7)
- 4-(2-Aminoethyl)-1-ethylazepan-4-ol (CAS 1526118-80-8)
- 6,7-difluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 865106-46-3)
- 5-[(3-amino-1H-pyrazol-1-yl)methyl]-2-furoic acid,HCl (CAS 1431963-63-1)
- (S)-Diallyl 2-aminosuccinate 4-methylbenzenesulfonate (CAS 125229-60-9)
- 2-(2-methoxyphenyl)-2-morpholin-4-ylacetonitrile (CAS 37673-08-8)
- Diethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate (CAS 1029689-54-0)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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