rac 8-Hydroxy Efavirenz-d4 CAS 1246812-30-5
| CAS No. | 1246812-30-5 |
| Molecular Formula | - |
| Molecular Weight | 335.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies rac 8-Hydroxy Efavirenz-d4 (CAS 1246812-30-5), a certified reference material (molecular formula C14H5D4ClF3NO3, MW 335.70 g/mol) for analytical method development and quality control.
Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, rac 8-Hydroxy Efavirenz-d4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rac 8-Hydroxy Efavirenz-d4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H5D4ClF3NO3 |
| Molecular Weight | 335.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related rac Standards
- 8-Hydroxy-Efavirenz D4 (CAS 1217771-47-5)
- S(+)-Hydroxy chloroquine Diphosphate (CAS 158749-76-9)
- 4-Hydroxy-N-[(4-methoxyphenyl)methyl]-N-(propan-2-yl)benzene-1-sulfonamide (CAS 1881290-54-5)
- 6-Hydroxy-7-phenyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one (CAS 859141-72-3)
- 2-hydroxy-5-[(2,4,6-trimethylphenyl)sulfamoyl]benzoic acid 670266-31-6 (CAS 670266-31-6)
- 1-(4-Hydroxy-6-methylpyrimidin-2-yl)-3-(4-phenoxyphenyl)guanidine (CAS 510738-21-3)
- 6-Hydroxy-2-[(5-methoxy-1-methyl-1H-indol-3-yl)methylidene]-7-methyl-2,3-dihydro-1-benzofuran-3-one (CAS 929339-33-3)
- (3'-Hydroxy-5'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261985-14-1)
Recommended Standards
- N-(4-Chlorobenzyl)-3,5-dinitrobenzamide (CAS 446855-41-0)
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- 2-(3-(3-Chlorophenyl)-2-oxoimidazolidin-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1257548-03-0)
- Difloxacin EP Impurity G (CAS 98105-79-4)
- Etoxazole (CAS 153233-91-1)
- (2-Methylquinolin-6-yl)methanamine (CAS 1369207-07-7)
- Maltononaose (CAS 6471-60-9)
- Benzyl-PEG2-ethanol (CAS 2055300-50-8)
- 2-methyl-6-nitro-4H-3,1-benzoxazin-4-one (CAS 10073-89-9)
- 5-(2,5-Difluorophenyl)pyrrolidin-3-ol hydrochloride (CAS 1423033-97-9)
- (S)-4-((3,6-bis(4-methoxyphenyl)-9H-carbazol-9-yl)methyl)-2-methyl-4,5-dihydrooxazole (CAS 2357080-07-8)
- 2,3,4,5-Tetrafluoropyridine (CAS 3512-16-1)
- 3-Amino-4-phenyl-1H-1,2,4-triazol-5(4H)-one (CAS 1739-21-5)
- Cyclolinopeptide B (CAS 193139-41-2)
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