Lornoxicam impurity 53 CAS 1246819-40-8
| CAS No. | 1246819-40-8 |
| Molecular Formula | C12H8ClN3O6S3 |
| Molecular Weight | 421.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lornoxicam impurity 53 (CAS 1246819-40-8) is a certified pharmaceutical impurity reference standard with the molecular formula C12H8ClN3O6S3 and a molecular weight of 421.86 g/mol.
Based on its molecular formula C12H8ClN3O6S3, Lornoxicam impurity 53 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 421.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O6S3 |
| Molecular Weight | 421.86 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related Lornoxicam Standards
- Lornoxicam impurity 54 (CAS 1246818-50-7)
- Lornoxicam Impurity 21 (CAS CATO-C4X-201621)
- Lornoxicam impurity 61 (CAS CATO-C4X-201661)
- Lornoxicam Impurity 80 (CAS CATO-C4X-201680)
- Lornoxicam Impurity 81 (CAS 2763743-17-3)
- Lornoxicam Impurity 10 (CAS CATO-C4X-201610)
- Lornoxicam Impurity 104 (CAS CATO-C4X-2016104)
- Lornoxicam Impurity 15 (CAS CATO-C4X-201615)
Recommended Standards
- N-(4-(((4-chlorophenyl)thio)methyl)phenyl)-4-(trifluoromethyl)benzamide (CAS 321431-96-3)
- (S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-(4-chloro-phenyl)-propionic acid (CAS 1280787-11-2)
- 4-Chloro-N-(4-(((3-(trifluoromethyl)phenyl)thio)methyl)phenyl)benzamide (CAS 338398-62-2)
- (R)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-(4-chloro-phenyl)-propionic acid (CAS 1280787-14-5)
- Ipratropium Bromide EP Impurity A (CAS 58005-18-8)
- Dexamethasone Impurity 102 (CAS CATO-C4X-1165102)
- Delamanid Impurity 7 (CAS CATO-C4X-25147)
- 2,5-Dichloro-4-(difluoromethoxy)benzylamine (CAS 1806353-12-7)
- 4-Methyl-N-(thietan-3-yl)pyridin-2-amine (CAS 1866468-81-6)
- (2-Bromophenethoxy)(t-butyl)dimethylsilane (CAS 181021-20-5)
- 2-(1,5-Dimethyl-2-oxoindolin-3-yl)acetonitrile (CAS 1808178-70-2)
- 4-(Methoxycarbonyl)-1-methyl-1h-pyrazole-5-carboxylic acid (CAS 1131912-84-9)
- 2-(3-Chlorophenyl)-1-ethyl-6-oxopiperidine-3-carboxylic acid (CAS 1212241-27-4)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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