10,20-Di-O-methoxymethyl SN-38 1246820-40-5 CAS 1246820-40-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1246820-40-5
Molecular FormulaC26H28N2O7
Molecular Weight480.51 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

10,20-Di-O-methoxymethyl SN-38
1246820-40-5 CAS 1246820-40-5 chemical structure

Description

The occurrence of 10,20-Di-O-methoxymethyl SN-38 1246820-40-5 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 10,20-Di-O-methoxymethyl SN-38 1246820-40-5 (CAS 1246820-40-5), a certified reference material (molecular formula C26H28N2O7, MW 480.51 g/mol) for analytical method development and quality control.

The molecular framework of 10,20-Di-O-methoxymethyl SN-38 1246820-40-5 (C26H28N2O7) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC26H28N2O7
Molecular Weight480.51 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms2

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