6-Fluoro-N-(thiophen-2-ylmethyl)pyridin-2-amine CAS 1247738-89-1
| CAS No. | 1247738-89-1 |
| Molecular Formula | C10H9FN2S |
| Molecular Weight | 208.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-N-(thiophen-2-ylmethyl)pyridin-2-amine (CAS 1247738-89-1) is a high-purity analytical reference standard with the molecular formula C10H9FN2S and a molecular weight of 208.26 g/mol.
The molecular framework of 6-Fluoro-N-(thiophen-2-ylmethyl)pyridin-2-amine (C10H9FN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Fluoro-N-(thiophen-2-ylmethyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9FN2S |
| Molecular Weight | 208.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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- 4-Fluoro-N-(thiazol-5-ylmethyl)aniline (CAS 1342182-42-6)
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- 1-(5-Fluoro-3-methyl-benzo-[b]thiophen-2-yl)-ethanone (CAS 51828-34-3)
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Recommended Standards
- 1-Cyclopentyl-5-ethyl-1h-pyrazole-4-carboxylic acid (CAS 1247493-90-8)
- 2-((Tetrahydro-2H-pyran-4-yl)methoxy)pyridin-3-amine (CAS 1247781-62-9)
- 1-Methyl-N-(pyrrolidin-2-ylmethyl)-1h-pyrazole-4-carboxamide (CAS 1247475-90-6)
- 2-[Cyclopropyl-(2-hydroxy-ethyl)-amino]-1-(1H-pyrrol-2-yl)-ethanone (CAS 1247930-31-9)
- 2-(Difluoromethyl)-6-methyl-5-nitropyridine-3-carboxylic acid (CAS 1806039-76-8)
- 5-(4-Fluorophenyl)-1-methyl-1H-imidazol-2-amine (CAS 787586-82-7)
- Propargyl-PEG5-NHS ester (CAS 1393330-40-9)
- N,1,5-Trimethyl-1H-1,2,3-triazole-4-carboxamide (CAS 388623-89-0)
- 3-(2,3-dihydro-1,4-benzodioxin-5-yl)-1,2-oxazol-5-amine (CAS 1156753-33-1)
- 4-Amino-6-hydroxypyrimidine-2-carboxylic acid (CAS 5177-21-9)
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- Amorolfine Impurity 36 (CAS CATO-C4X-154236)
- N-(2-Chlorobenzyl)-2-(2,5-dimethylphenoxy)-1-ethanamine (CAS 1040684-29-4)
- Insulin B (22-25) (CAS 34367-73-2)
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