3-methyl-3-[4-(trifluoromethyl)phenyl]pyrrolidine CAS 1248089-24-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-methyl-3-[4-(trifluoromethyl)phenyl]pyrrolidine.

3-methyl-3-[4-(trifluoromethyl)phenyl]pyrrolidine (CAS 1248089-24-8), molecular formula C12H14F3N and molecular weight 229.24 g/mol, is a CATO reference standard with documented purity and traceability.

3-methyl-3-[4-(trifluoromethyl)phenyl]pyrrolidine (C12H14F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-methyl-3-[4-(trifluoromethyl)phenyl]pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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