2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid CAS 1248094-19-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1248094-19-0
Molecular FormulaC8H4Cl2F2O2
Molecular Weight241.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid CAS 1248094-19-0 chemical structure

Description

The occurrence of 2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid (CAS 1248094-19-0) is a high-purity analytical reference standard with the molecular formula C8H4Cl2F2O2 and a molecular weight of 241.02 g/mol.

2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid (C8H4Cl2F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2,3-Dichlorophenyl)-2,2-difluoroacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H4Cl2F2O2
Molecular Weight241.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/Cl-containing

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