1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one CAS 1248109-22-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1248109-22-9
Molecular FormulaC11H12BrClO2
Molecular Weight291.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one CAS 1248109-22-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 291.57 g/mol gives 1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one (CAS 1248109-22-9), a certified reference material (molecular formula C11H12BrClO2, MW 291.57 g/mol) for analytical method development and quality control.

The molecular framework of 1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one (C11H12BrClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(3-Bromo-5-chloro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H12BrClO2
Molecular Weight291.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl/Br-containing

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