4-Bromo-2-(2-fluoroethoxy)pyridine CAS 1248622-95-8
| CAS No. | 1248622-95-8 |
| Molecular Formula | C7H7BrFNO |
| Molecular Weight | 220.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-2-(2-fluoroethoxy)pyridine.
CATO supplies 4-Bromo-2-(2-fluoroethoxy)pyridine (CAS 1248622-95-8), a certified reference material (molecular formula C7H7BrFNO, MW 220.04 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-2-(2-fluoroethoxy)pyridine (C7H7BrFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2-(2-fluoroethoxy)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BrFNO |
| Molecular Weight | 220.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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- 4-Bromo-2-fluoro-5-methoxyaniline (CAS 108310-38-9)
- 3-Bromo-5-fluoro-2-methoxyaniline (CAS 1096884-89-7)
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-ol (CAS 1111637-73-0)
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Recommended Standards
- (2-Amino-6-bromo-3-fluorophenyl)methanol (CAS 1227958-14-6)
- 4-Bromo-2-fluoro-6-methoxyaniline (CAS 1261216-27-6)
- 4-(Bromomethyl)-5-fluoro-2-methoxypyridine (CAS 1227604-29-6)
- 4-Bromo-2-fluoro-3-methoxyaniline (CAS 1272719-19-3)
- N-(2-Oxotetrahydrofuran-3-yl)palmitamide (CAS 98206-81-6)
- 5-Fluoro-4-methyl-3-nitrobenzene-1,2-diamine (CAS 147285-84-5)
- Methyl 2-(benzylamino)-2-methylpropanoate (CAS 78002-18-3)
- (3-(Methylamino)-4-nitrophenyl)methanol (CAS 1228182-77-1)
- 5-(Cyclohexylmethyl)-2-hydroxy-N-methylbenzamide (CAS 1243439-64-6)
- Dencichine (CAS 5302-45-4)
- Methyl 4-amino-2-fluoro-5-methylbenzoate (CAS 1427398-87-5)
- 5-trifluoromethyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1256820-22-0)
- 6-Bromo-4-chloro-8-fluoroquinazoline (CAS 1565583-08-5)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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