Methyl rel-(E)-7-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4- (4-fluorophenyl)-pyrid-3-yl]-3,5-dihydroxy-6-heptenoate CAS 124863-86-1

Purity 97%+In StockPharmaceutical Standards
CAS No.124863-86-1
Molecular FormulaC32H48FNO5Si
Molecular Weight573.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl rel-(E)-7-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4- (4-fluorophenyl)-pyrid-3-yl]-3,5-dihydroxy-6-heptenoate CAS 124863-86-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl rel-(E)-7-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4- (4-fluorophenyl)-pyrid-3-yl]-3,5-dihydroxy-6-heptenoate.

Methyl rel-(E)-7-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4- (4-fluorophenyl)-pyrid-3-yl]-3,5-dihydroxy-6-heptenoate (CAS 124863-86-1), molecular formula C32H48FNO5Si and molecular weight 573.81 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl rel-(E)-7-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4- (4-fluorophenyl)-pyrid-3-yl]-3,5-dihydroxy-6-heptenoate (C32H48FNO5Si) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC32H48FNO5Si
Molecular Weight573.81 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1

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