(2-Hydroxyquinolin-3-yl)methanesulfonyl chloride CAS 1249135-11-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1249135-11-2
Molecular FormulaC10H8ClNO3S
Molecular Weight257.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Hydroxyquinolin-3-yl)methanesulfonyl chloride CAS 1249135-11-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 257.69 g/mol gives (2-Hydroxyquinolin-3-yl)methanesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2-Hydroxyquinolin-3-yl)methanesulfonyl chloride (CAS 1249135-11-2) is a high-purity analytical reference standard with the molecular formula C10H8ClNO3S and a molecular weight of 257.69 g/mol.

(2-Hydroxyquinolin-3-yl)methanesulfonyl chloride (C10H8ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2-Hydroxyquinolin-3-yl)methanesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H8ClNO3S
Molecular Weight257.69 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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