2-(5-Chloro-2-methoxyphenyl)-2,2-difluoroacetic acid CAS 1249203-61-9
| CAS No. | 1249203-61-9 |
| Molecular Formula | C9H7ClF2O3 |
| Molecular Weight | 236.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.60 g/mol gives 2-(5-Chloro-2-methoxyphenyl)-2,2-difluoroacetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(5-Chloro-2-methoxyphenyl)-2,2-difluoroacetic acid (CAS 1249203-61-9), molecular formula C9H7ClF2O3 and molecular weight 236.60 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H7ClF2O3, 2-(5-Chloro-2-methoxyphenyl)-2,2-difluoroacetic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(5-Chloro-2-methoxyphenyl)-2,2-difluoroacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF2O3 |
| Molecular Weight | 236.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
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- 2-(4-Chloro-3-methoxyphenyl)-2,2-difluoroacetic acid (CAS 1540654-98-5)
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- 2-(4-Chloro-2-methylphenoxy)-2,2-difluoroacetic acid (CAS 400087-82-3)
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Recommended Standards
- 3-(2-Chlorophenyl)-2,2-difluoro-3-hydroxypropanoic Acid (Mixture of Diastereomers) (CAS 1250734-08-7)
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- 4-(Difluoromethoxy)-3-methoxybenzoyl chloride (CAS 162401-79-8)
- 2-Chloro-5-(pentafluoroethyl)thiophene (CAS 1429056-29-0)
- 1-(4-fluorobenzenesulfonyl)pyrrolidine (CAS 157187-14-9)
- 5-Oxo-5-(2,4,5-trimethoxyphenyl)pentanoic acid (CAS 92865-60-6)
- 2-[(4-tert-butylphenyl)methyl]propanedioic acid (CAS 683215-55-6)
- 2-(1-Methyl-1H-1,2,4-triazol-5-yl)benzoic Acid (CAS 1250530-15-4)
- Methyl (R)-2-(1-((tert-butoxycarbonyl)amino)ethyl)-5-methyloxazole-4-carboxylate (CAS 343339-23-1)
- 3-Hydroxy-8-methylquinolin-2(1H)-one (CAS 861580-69-0)
- 4-((2,5-Dimethylphenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 900011-49-6)
- Ethyl 3-Oxo-3-[3-(trifluoromethoxy)phenyl]propanoate (CAS 642451-74-9)
- (3-Nitro-1H-pyrazol-1-yl)acetaldehyde (CAS 1015939-63-5)
- Hexapeptide-9 (CAS 1228371-11-6)
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