4-(Piperidin-2-yl)pyrimidin-2-amine CAS 1249234-64-7
| CAS No. | 1249234-64-7 |
| Molecular Formula | C9H14N4 |
| Molecular Weight | 178.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Piperidin-2-yl)pyrimidin-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Piperidin-2-yl)pyrimidin-2-amine (CAS 1249234-64-7), molecular formula C9H14N4 and molecular weight 178.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Piperidin-2-yl)pyrimidin-2-amine (C9H14N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14N4 |
| Molecular Weight | 178.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Piperidin Standards
- 2-(Piperidin-1-yl)pyrimidin-5-amine (CAS 1086378-61-1)
- 4-(Piperidin-3-yloxy)pyridine (CAS 1171481-61-0)
- 3-(Piperidin-1-yl)pyrazin-2-amine (CAS 117719-15-0)
- 4-(piperidin-4-yl)pyrimidin-2-amine (CAS 1211532-88-5)
- N-(Piperidin-4-yl)pyrimidin-4-amine (CAS 1211585-01-1)
- 4-(piperidin-3-yl)pyrimidin-2-amine (CAS 1250024-30-6)
- 3-(Piperidin-2-yl)pyridin-2(1H)-one (CAS 1270529-00-4)
- 5-(Piperidin-2-yl)pyridin-2-ol (CAS 1270529-38-8)
Recommended Standards
- 1-(4-Ethoxyphenyl)cyclopropan-1-ol (CAS 1249123-59-8)
- N-((2-methoxypyridin-3-yl)methyl)cyclopropanamine (CAS 1249771-15-0)
- N-((6-methoxypyridin-3-yl)methyl)cyclopropanamine (CAS 1249037-91-9)
- 1-(Pyrimidin-4-yl)piperidin-3-amine (CAS 1249914-20-2)
- 2-Chloro-1-{1-[(2-fluorophenyl)methyl]-2,5-dimethyl-1h-pyrrol-3-yl}ethan-1-one (CAS 887683-66-1)
- tert-Butyl 2-benzoyl-3-phenyl-1-pyrrolidinecarboxylate (CAS 1424939-33-2)
- 2-Bromo-3-methylbut-2-en-1-amine (CAS 111463-45-7)
- 3,4-Dihydro-1H-benzo[d][1,2]thiazine 2,2-dioxide (CAS 33183-87-8)
- 5-Fluoro-2-[(1-methyl-1h-pyrazol-4-yl)methoxy]aniline (CAS 1006468-29-6)
- 2-Bromo-6-chloro-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1010101-11-7)
- O-(2-Methoxypropan-2-yl)hydroxylamine (CAS 103491-33-4)
- Methyl 3,4-difluoro-2-methoxybenzoate (CAS 948833-75-8)
- 2-Amino-N-(2-((4-chloro-2-methylphenyl)amino)-2-oxoethyl)acetamide hydrochloride (CAS 1832872-91-9)
- Smac-N7 Peptide (CAS 401913-57-3)
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