1-(6-Chloropyrimidin-4-yl)-4-methyl-1,4-diazepane CAS 1249360-05-1
| CAS No. | 1249360-05-1 |
| Molecular Formula | C10H15ClN4 |
| Molecular Weight | 226.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(6-Chloropyrimidin-4-yl)-4-methyl-1,4-diazepane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(6-Chloropyrimidin-4-yl)-4-methyl-1,4-diazepane (CAS 1249360-05-1) is a high-purity analytical reference standard with the molecular formula C10H15ClN4 and a molecular weight of 226.71 g/mol.
The molecular framework of 1-(6-Chloropyrimidin-4-yl)-4-methyl-1,4-diazepane (C10H15ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H15ClN4 |
| Molecular Weight | 226.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropyrimidin Standards
- (1-(2-Chloropyrimidin-4-yl)piperidin-4-yl)methanamine (CAS 876144-87-5)
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- 1-(6-Chloropyrimidin-4-yl)pyrrolidine-2-carboxamide (CAS 1250424-99-7)
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- [1-(6-chloropyrimidin-4-yl)piperidin-2-yl]methanol (CAS 1247580-97-7)
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Recommended Standards
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- 4-Chloro-6-(3-methylpiperidin-1-yl)pyrimidin-2-amine (CAS 1158375-02-0)
- 2-Chloro-3-(4-ethylpiperazin-1-yl)pyrazine (CAS 1250486-53-3)
- 1-Ethyl-5-oxopyrrolidine-2-carboxylic acid (CAS 1001390-60-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com