3-Hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid CAS 1249467-87-5
| CAS No. | 1249467-87-5 |
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 1249467-87-5), molecular formula C10H9F3O3 and molecular weight 234.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 3-Hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 234.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 1-(4-Hydroxy-3-(trifluoromethoxy)phenyl)propan-2-one (CAS 1017082-14-2)
- 2-Hydroxy-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 1207255-93-3)
- 3-Hydroxy-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 1249638-91-2)
- 2-hydroxy-2-[2-(trifluoromethyl)phenyl]propanoic acid (CAS 1250334-60-1)
- Methyl 2-hydroxy-2-[2-(trifluoromethyl)phenyl]acetate (CAS 1250424-06-6)
- Ethyl 2-hydroxy-5-(trifluoromethyl)benzoate (CAS 1261620-38-5)
- (R)-2-Hydroxy-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 1331101-87-1)
- 4-Hydroxy-6-nitroquinoline-2-carboxylic acid (CAS 134785-84-5)
Recommended Standards
- 2-[3-(2,2,2-trifluoroethoxy)phenyl]acetic acid (CAS 1248311-33-2)
- 2-(2-(Trifluoromethoxy)phenyl)propanoic acid (CAS 1247172-40-2)
- 5-(2-Nitrophenyl)isoxazole-3-carboxylic Acid (CAS 1232028-11-3)
- 2-(2-Nitrophenyl)oxazole-4-carboxylic acid (CAS 1220040-17-4)
- 1-Methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 1239164-77-2)
- 4-(2-Methoxyphenyl)piperidin-4-ol (CAS 81950-85-8)
- (2E)-3-(3,4-Dimethoxyphenyl)-1-(2-methylphenyl)prop-2-en-1-one (CAS 1354942-41-8)
- 3-(2-fluorophenyl)but-2-enoic acid (CAS 1130-95-6)
- Urapidil Impurity 9 (CAS 108997-11-1)
- 1-(4-Chlorophenyl)-2-(phenylsulfonyl)ethan-1-one (CAS 38488-19-6)
- 2,5-diazabicyclo[2.2.1]heptane;dihydrochloride (CAS 89487-38-7)
- 7-Hydroxy-6-isopropyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 1310261-25-6)
- 1-(3-(Isopentylthio)phenyl)ethan-1-one (CAS 1342657-27-5)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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