2-(4-Ethyl-1-hydroxycyclohexyl)-2,2-difluoroacetic acid CAS 1249661-13-9
| CAS No. | 1249661-13-9 |
| Molecular Formula | C10H16F2O3 |
| Molecular Weight | 222.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Ethyl-1-hydroxycyclohexyl)-2,2-difluoroacetic acid (CAS 1249661-13-9), molecular formula C10H16F2O3 and molecular weight 222.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-Ethyl-1-hydroxycyclohexyl)-2,2-difluoroacetic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Ethyl-1-hydroxycyclohexyl)-2,2-difluoroacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H16F2O3 |
| Molecular Weight | 222.23 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 2-(4-Hydroxycyclohexyl)pyrimidine-5-carboxylic acid (CAS 1447607-31-9)
- 3-{[(4-hydroxycyclohexyl)amino]methyl}phenol (CAS 1019623-12-1)
- N-(4-Hydroxycyclohexyl)benzamide (CAS 13941-93-0)
- N-(3-Hydroxycyclohexyl)benzamide (CAS 13941-94-1)
- Methyl 1-(2-hydroxycyclohexyl)-1h-1,2,3-triazole-4-carboxylate (CAS 1197579-14-8)
- trans-(4-hydroxycyclohexyl) benzoate (CAS 917771-54-1)
- 1-(4-Hydroxycyclohexyl)piperidine-4-carboxylic acid (CAS 1216381-40-6)
- (4-Hydroxycyclohexyl)carbamic Acid tert-Butyl Ester 224309-64-2 4-(Boc-amino)cyclohexanol 4-(tert-Butoxycarbonylamino)cyclohexanol B4714 tert-Butyl (4-Hydroxycyclohexyl)carbamate (CAS 224309-64-2)
Recommended Standards
- 2,2,2-Trifluoro-1-(4-(methylthio)phenyl)ethan-1-ol (CAS 122035-81-8)
- 2,3-Dimethyl-4-((trifluoromethyl)thio)phenol (CAS 129644-70-8)
- Osmium(iv)oxide (CAS 12036-02-1)
- 4,4-Difluoro-1-(2-methoxyethyl)cyclohexane-1-carboxylic acid (CAS 1389315-15-4)
- 4-Bromo-5-methylpyridine-2-acetic acid (CAS 1807198-39-5)
- 4-(4-Fluorophenyl)-4-methylpentan-2-one (CAS 565-37-7)
- 4-{5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl}-1,3-thiazol-2-amine (CAS 868387-43-3)
- 6-Chloro-1H-imidazo[4,5-b]pyridine (CAS 21422-66-2)
- Methyl 4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxylate (CAS 1086386-53-9)
- 2-Amylpyridine (CAS 2294-76-0)
- (1s,2r)-2-(2-Fluorophenoxy)cyclopentan-1-amine (CAS 1486473-02-2)
- Methyl 4'-(dimethoxymethyl)-[1,1'-biphenyl]-3-carboxylate (CAS 2444046-05-1)
- (2Z)-2-[(2,4-Dichlorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one (CAS 53898-72-9)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
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