2-((4-(Trifluoromethyl)benzyl)oxy)ethanamine CAS 1249911-92-9
| CAS No. | 1249911-92-9 |
| Molecular Formula | C10H12F3NO |
| Molecular Weight | 219.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((4-(Trifluoromethyl)benzyl)oxy)ethanamine (C10H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-((4-(Trifluoromethyl)benzyl)oxy)ethanamine (CAS 1249911-92-9), molecular formula C10H12F3NO and molecular weight 219.20 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12F3NO |
| Molecular Weight | 219.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 1-(4-(Trifluoromethyl)phenoxy)propan-2-amine (CAS 89763-86-0)
- 2-({[2-(trifluoromethyl)phenyl]methyl}amino)ethan-1-ol (CAS 774555-36-1)
- 2-({[4-(trifluoromethyl)phenyl]methyl}amino)ethan-1-ol (CAS 948588-69-0)
- 2-(2-(Trifluoromethyl)phenoxy)propan-1-amine (CAS 883543-02-0)
- 2-(3-(Trifluoromethyl)phenoxy)propan-1-amine (CAS 886763-47-9)
- 2-(3-Trifluoromethyl-benzylamino)-ethanol (CAS 912291-17-9)
- 2-(4-(Trifluoromethyl)phenoxy)propan-1-amine (CAS 886763-49-1)
- Methyl({2-[4-(trifluoromethyl)phenoxy]ethyl})amine (CAS 467463-22-5)
Recommended Standards
- 2-(1-Methyl-1h-1,2,4-triazol-5-yl)-4-nitroaniline (CAS 1249874-29-0)
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- n-((1h-Pyrazol-3-yl)methyl)-3-nitropyridin-2-amine (CAS 1249818-03-8)
- 3,3,3-Trifluoro-1-(3-methoxyphenyl)propan-1-amine (CAS 1250591-36-6)
- N-(3-Hydroxy-2-(methylamino)phenyl)methanesulfonamide (CAS 1243441-13-5)
- 4-Fluoro-2-iodobenzophenone (CAS 138504-31-1)
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- Arachidonic acid sodium salt from porcine liver, >=99% (capillary GC), waxy solid (CAS 6610-25-9)
- (2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole (CAS 2247162-97-4)
- 3-Hydroxy-5-methanesulfonyl-1,2-thiazole-4-carbonitrile (CAS 25629-56-5)
- Phentolamine Impurity 14 (CAS CATO-C4X-224714)
- tert-Butyl 7,7-dimethyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (CAS 1820937-65-2)
- (E)-1-(6-bromopyridin-2-yl)-3-(dimethylamino)prop-2-en-1-one (CAS 638197-51-0)
- Osteoblast-Adhesive Peptide (CAS 193613-75-1)
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