Pentoxyverine EP Impurity B Hydrochloride CAS 125-85-9
| CAS No. | 125-85-9 |
| Molecular Formula | C18H27NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pentoxyverine EP Impurity B Hydrochloride (C18H27NO2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Pentoxyverine EP Impurity B Hydrochloride (CAS 125-85-9, C18H27NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Pentoxyverine EP Impurity B Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27NO2 HCl |
| Molecular Weight | 325.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pentoxyverine Standards
- Pentoxyverine Impurity 1 (CAS 105539-06-8)
- Pentoxyverine-d8 (CAS 1329797-10-5)
- Pentoxyverine Impurity 22 (CAS 13877-99-1)
- Pentoxyverine Impurity 11 (CAS 1421930-88-2)
- Pentoxyverine impurity 18 (CAS 1421930-96-2)
- Pentoxyverine Citrate (CAS 23142-01-0)
- Pentoxyverine Impurity 21 (CAS 334504-92-6)
- Pentoxyverine Impurity 4 (CAS 5296-89-9)
Recommended Standards
- Neticonazole impurity 11 (CAS 56986-82-4)
- Methylene blue Impurity 6 (CAS 4727-46-2)
- Empagliflozin Impurity 114 (CAS 1459754-32-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com