1-(2,2,2-Trifluoroethyl)-1h-1,3-benzodiazol-5-amine CAS 1250199-46-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2,2,2-Trifluoroethyl)-1h-1,3-benzodiazol-5-amine.

1-(2,2,2-Trifluoroethyl)-1h-1,3-benzodiazol-5-amine (CAS 1250199-46-2), molecular formula C9H8F3N3 and molecular weight 215.18 g/mol, is a CATO reference standard with documented purity and traceability.

1-(2,2,2-Trifluoroethyl)-1h-1,3-benzodiazol-5-amine (C9H8F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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