1-(2,4-Difluorobenzyl)piperazin-2-one CAS 1250306-29-6
| CAS No. | 1250306-29-6 |
| Molecular Formula | C11H12F2N2O |
| Molecular Weight | 226.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(2,4-Difluorobenzyl)piperazin-2-one (CAS 1250306-29-6) is a high-purity analytical reference standard with the molecular formula C11H12F2N2O and a molecular weight of 226.22 g/mol.
1-(2,4-Difluorobenzyl)piperazin-2-one (C11H12F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H12F2N2O |
| Molecular Weight | 226.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzyl Standards
- (S)-3-(2,3-Difluorobenzyl)piperazin-2-one (CAS 1240585-78-7)
- (S)-3-(3,4-Difluorobenzyl)piperazin-2-one (CAS 1240586-02-0)
- (S)-3-(2,4-Difluorobenzyl)piperazin-2-one (CAS 1240587-65-8)
- (R)-3-(2,5-Difluorobenzyl)piperazin-2-one (CAS 1240590-50-4)
- 3-(3,5-Difluorobenzyl)piperazin-2-one (CAS 1246548-59-3)
- 3,5-difluorobenzyl cyclobutane-1-carboxylate (CAS 259099-74-6)
- 1-(3,5-Difluorobenzyl)-1,3-dihydro-2H-imidazole-2-thione (CAS 95333-81-6)
- 5-(3,4-difluorobenzyl)-1,3-thiazol-2-amine (CAS 937617-31-7)
Recommended Standards
- 1-(2,3-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 1260675-77-1)
- 1-(2,6-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 1260759-21-4)
- 1-(2,4-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 1260784-54-0)
- 1-(2,5-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 1260826-90-1)
- Dibutyldecylphosphonate (CAS 36378-71-9)
- N-(2-hydroxyethyl)-3-iodo-N-methylbenzamide (CAS 1178947-96-0)
- 5-Bromopyridine-3-carbothioamide (CAS 890093-82-0)
- Fmoc-5-Chloro-L-tryptophan (CAS 1257849-07-2)
- 5-Ethylpyrimidin-4-ol (CAS 25198-98-5)
- 3,3-Difluoro-2,2-dimethylbutan-1-ol (CAS 1955548-09-0)
- Methyl 3-hydroxy-5-methyl-1H-indole-2-carboxylate (CAS 113525-13-6)
- 3-chloro-2,6-dimethoxybenzene-1-sulfonyl chloride (CAS 145980-90-1)
- 2-Propylbenzo[d]oxazol-5-amine (CAS 886361-62-2)
- Peptide Impurity 34 (CAS 21282-09-7)
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