| CAS No. | 1250787-67-7 |
| Molecular Formula | C9H8F4O2 |
| Molecular Weight | 224.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
As a certified reference material (CRM), 2,2,2-Trifluoro-1-(5-fluoro-2-methoxyphenyl)ethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,2,2-Trifluoro-1-(5-fluoro-2-methoxyphenyl)ethan-1-ol (CAS 1250787-67-7), molecular formula C9H8F4O2 and molecular weight 224.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,2,2-Trifluoro-1-(5-fluoro-2-methoxyphenyl)ethan-1-ol (C9H8F4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
| Molecular Formula | C9H8F4O2 |
| Molecular Weight | 224.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |