3-Hydroxymethyl-5,6-Dihydro-8H-[1,2,4]Triazolo[4,3-A]Pyrazine-7-Carboxylic Acid Tert-Butyl Ester CAS 1251002-77-3
| CAS No. | 1251002-77-3 |
| Molecular Formula | C11H18N4O3 |
| Molecular Weight | 254.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 3-Hydroxymethyl-5,6-Dihydro-8H-[1,2,4]Triazolo[4,3-A]Pyrazine-7-Carboxylic Acid Tert-Butyl Ester is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Hydroxymethyl-5,6-Dihydro-8H-[1,2,4]Triazolo[4,3-A]Pyrazine-7-Carboxylic Acid Tert-Butyl Ester (CAS 1251002-77-3), molecular formula C11H18N4O3 and molecular weight 254.29 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18N4O3 |
| Molecular Weight | 254.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Hydroxymethyl Standards
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- (S)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(4-methylcyclohexyl)acetamide (CAS 1311907-52-4)
- Methyl 3-((4-(hydroxymethyl)piperidin-1-yl)methyl)furan-2-carboxylate (CAS 1258698-52-0)
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Recommended Standards
- Tert-butyl 3-(hydroxymethyl)-6,7-dihydro-[1,2,3]triazolo[1,5-a]pyrazine-5(4h)-carboxylate (CAS 1251002-72-8)
- 5-(6-Methoxyimidazo[1,2-b]pyridazin-2-yl)-2-methylaniline (CAS 1286732-85-1)
- 1-(8-Methoxyquinolin-2-yl)-3-methyl-1H-pyrazol-5-amine (CAS 1225743-30-5)
- n-[2-(1h-indol-3-yl)ethyl]-1h-pyrazole-4-carboxamide (CAS 1306106-76-2)
- 7-(tert-Butyl)indoline (CAS 1315376-61-4)
- (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(((3R,3aR,6S,6aS)-6-(nitrooxy)hexahydrofuro[3,2-b]furan-3-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid (CAS 89576-61-4)
- Methyl 2-(3-methyl-1,2,4-oxadiazol-5-yl)acetate (CAS 55152-01-7)
- 1-((3,4-Dimethoxyphenyl)sulfonyl)-4-ethylpiperazine (CAS 676642-62-9)
- Ethyl 8-aminochromane-2-carboxylate (CAS 1047721-79-8)
- (1s,3s)-3-(4-(Trifluoromethyl)phenyl)cyclobutan-1-amine (CAS 1812174-93-8)
- Methyl 2-amino-4-isobutylthiophene-3-carboxylate (CAS 183562-37-0)
- 3-((1-(Tert-butoxycarbonyl)azetidin-3-yl)oxy)propanoic acid (CAS 895126-65-5)
- 6-Bromo-3-iodo-7-methyl-1h-indazole (CAS 1965309-01-6)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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