cis-tert-Butyl-3,3a,4,5-tetrahydro-1H-pyrrolo-[3,4-c]isoquinoline-2(9bH)-carboxylate CAS 1251003-76-5
| CAS No. | 1251003-76-5 |
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
cis-tert-Butyl-3,3a,4,5-tetrahydro-1H-pyrrolo-[3,4-c]isoquinoline-2(9bH)-carboxylate (CAS 1251003-76-5) is a high-purity analytical reference standard with the molecular formula C16H22N2O2 and a molecular weight of 274.36 g/mol.
Structurally, cis-tert-Butyl-3,3a,4,5-tetrahydro-1H-pyrrolo-[3,4-c]isoquinoline-2(9bH)-carboxylate (C16H22N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 274.36 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Trans-1,2,3,3A,5,9B-Hexahydro-Pyrrolo[3,4-C]Isoquinoline-4-Carboxylic Acid Tert-Butyl Ester (CAS 1251002-37-5)
- (3AR*,8R*,8aR*)-tert-Butyl 8-amino-3,3a,8,8atetra-hydroindeno[2,1-c]pyrrole-2(1H)-carboxylate (CAS 1251007-19-8)
- tert-Butyl spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate (CAS 1251001-95-2)
- tert-Butyl (3aR,9bR)-1,3,3a,4,5,9b-hexahydropyrrolo[3,4-c]quinoline-2-carboxylate (CAS 1251017-31-8)
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 507462-26-2)
- 5-Chloro-8-fluoropyrido[3,4-b]pyrazine (CAS 1374652-17-1)
- 1,1'-(Propane-1,3-diylbis(4,1-phenylene))diethanone (CAS 6337-58-2)
- Methyl 2-(6-methylpyridin-2-yl)acetate (CAS 58532-56-2)
- (2R,3R)-3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)tetrahydrofuran-2-carboxylic acid (CAS 2140264-04-4)
- 5-Methyl-2-(pyridin-2-yl)indoline (CAS 595547-86-7)
- Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nε-tetradecanoyl-L-lysine (CAS 1128181-23-6)
- (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride (CAS 1929582-61-5)
- (R)-2-(3-(1-Aminoethyl)-2-fluorophenyl)-2,2-difluoroethanol (CAS 2359690-81-4)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com