4-(Trifluoromethyl)thiazole-2-carboximidamide hydrochloride CAS 1251166-15-0
| CAS No. | 1251166-15-0 |
| Molecular Formula | C5H4F3N3S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(Trifluoromethyl)thiazole-2-carboximidamide hydrochloride (CAS 1251166-15-0), a certified reference material (molecular formula C5H4F3N3SHCl, MW 231.62 g/mol) for analytical method development and quality control.
The molecular framework of 4-(Trifluoromethyl)thiazole-2-carboximidamide hydrochloride (C5H4F3N3SHCl) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4F3N3S HCl |
| Molecular Weight | 231.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
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- 2-Propenoic acid, 3-[3,4-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-, (2E) (CAS 203118-32-5)
- Dulaglutide (CAS 923950-08-7)
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