N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide CAS 1251647-47-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1251647-47-8
Molecular FormulaC19H17N3O3S
Molecular Weight367.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide CAS 1251647-47-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide.

N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide (CAS 1251647-47-8) is a high-purity analytical reference standard with the molecular formula C19H17N3O3S and a molecular weight of 367.42 g/mol.

Structurally, N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide (C19H17N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 367.42 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2-Methoxybenzyl)-5-oxo-2,3-dihydro-5H-thiazolo[2,3-b]quinazoline-8-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H17N3O3S
Molecular Weight367.42 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms3
Sulfur Atoms1

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