4-Cyclopropyl-5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine CAS 1251922-72-1
| CAS No. | 1251922-72-1 |
| Molecular Formula | C13H13FN2S |
| Molecular Weight | 248.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Cyclopropyl-5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine (CAS 1251922-72-1) is a high-purity analytical reference standard with the molecular formula C13H13FN2S and a molecular weight of 248.32 g/mol.
4-Cyclopropyl-5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine (C13H13FN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Cyclopropyl-5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13FN2S |
| Molecular Weight | 248.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Cyclopropyl Standards
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- 8-tert-Butyl-4-(3-fluorobenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-15-7)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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