2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetamide dihydrochloride CAS 1252036-94-4
| CAS No. | 1252036-94-4 |
| Molecular Formula | C12H16ClN3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetamide dihydrochloride (CAS 1252036-94-4), molecular formula C12H16ClN3OHCl and molecular weight 290.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetamide dihydrochloride (C12H16ClN3OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16ClN3O 2*HCl |
| Molecular Weight | 290.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 1-(4-Chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylic acid phenylamide (CAS 1000577-01-4)
- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
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- (S)-5-((5-Hydroxy-1H-indol-3-yl)methyl)imidazolidine-2,4-dione (CAS 109063-48-1)
- Dimethyl[(6-methyl-1H-indol-3-yl)methyl]amine (CAS 35998-04-0)
- 3-Bromo-6-chloro-7-iodoimidazo[1,2-b]pyridazin-8-amine (CAS 2664901-38-4)
- (1R,2S)-1,2-Diphenyl-2-(3-phenylureido)ethyl 2-(diphenylphosphino)benzoate (CAS 2920833-55-0)
- 4-Hydroxy-3-nitro-1,5-naphthyridine (CAS 85938-78-9)
- cis-3-Octene (CAS 14850-22-7)
- 2-((4-Fluorobenzyl)oxy)isoindoline-1,3-dione (CAS 76866-37-0)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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