6-Bromo-3-chloropicolinonitrile CAS 1252046-16-4
| CAS No. | 1252046-16-4 |
| Molecular Formula | C6H2BrClN2 |
| Molecular Weight | 217.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.45 g/mol gives 6-Bromo-3-chloropicolinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Bromo-3-chloropicolinonitrile (CAS 1252046-16-4) is a high-purity analytical reference standard with the molecular formula C6H2BrClN2 and a molecular weight of 217.45 g/mol.
6-Bromo-3-chloropicolinonitrile (C6H2BrClN2) contains a nitrile group, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Bromo-3-chloropicolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClN2 |
| Molecular Weight | 217.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-6-chloropyridine-2-carbonitrile, 97% (CAS 1053659-39-4)
- 5-Bromo-4-chloronicotinonitrile (CAS 1160923-98-7)
- 6-Bromo-2-chloronicotinonitrile (CAS 1171919-79-1)
- 4-Bromo-6-chloropicolinonitrile (CAS 1206247-90-6)
- 6-Bromo-4-chloropicolinonitrile (CAS 1206248-51-2)
- 5-Bromo-2-chloroisonicotinonitrile (CAS 1211515-17-1)
- 2-Bromo-5-chloroisonicotinonitrile (CAS 1211537-53-9)
- 5-Bromo-4-chloropyridine-2-carbonitrile (CAS 1256790-41-6)
Recommended Standards
- 6-Bromo-4-chloronicotinonitrile (CAS 1256790-67-6)
- 6-Bromo-5-chloronicotinonitrile (CAS 1256790-78-9)
- 6-Bromo-5-chloropyridine-2-carbonitrile (CAS 1256823-45-6)
- 5-Bromo-6-chloropicolinonitrile (CAS 1256823-65-0)
- 5-((Benzylthio)methyl)isoxazol-3(2H)-one (CAS 89660-73-1)
- 8-Bromo-5-chloroimidazo[1,5-a]pyridine-6-carbonitrile (CAS 2585650-35-5)
- ((2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-(phosphonooxy)tetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 4682-43-3)
- 3-[(3-Phenylpropoxy)methyl]piperidinehydrochloride (CAS 1050509-62-0)
- (2R)-2-amino-3-(oxan-4-yl)propanoic acid hydrochloride (CAS 1207447-38-8)
- Ethyl 1-cyclopropyl-5-methyl-1H-pyrazole-3-carboxylate (CAS 1639114-45-6)
- 5-Methyl-5-(trifluoromethyl)pyrrolidine-2,4-dione (CAS 1997200-27-7)
- 4-(Benzo[d]oxazol-2-yl)benzonitrile (CAS 838-33-5)
- 1,1-Dimethyl-1,2,3,4-tetrahydroisoquinoline (CAS 41565-85-9)
- Peptide Impurity 05 (CAS 2322924-83-2)
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