2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)nicotinamide CAS 125335-75-3

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)nicotinamide (CAS 125335-75-3) is a high-purity analytical reference standard with the molecular formula C10H13ClN2O2 and a molecular weight of 228.68 g/mol.

2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)nicotinamide (C10H13ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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