4-(Pyrrolidin-1-yl)benzenesulfonyl chloride CAS 125393-18-2

Purity 97%+In StockPharmaceutical Standards
CAS No.125393-18-2
Molecular FormulaC10H12ClNO2S
Molecular Weight245.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Pyrrolidin-1-yl)benzenesulfonyl chloride CAS 125393-18-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 245.73 g/mol gives 4-(Pyrrolidin-1-yl)benzenesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-(Pyrrolidin-1-yl)benzenesulfonyl chloride (CAS 125393-18-2), a certified reference material (molecular formula C10H12ClNO2S, MW 245.73 g/mol) for analytical method development and quality control.

The molecular framework of 4-(Pyrrolidin-1-yl)benzenesulfonyl chloride (C10H12ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H12ClNO2S
Molecular Weight245.73 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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