1-Cyclopropyl-3-methyl-1h-pyrazole-5-carboxylic acid CAS 1254199-92-2
| CAS No. | 1254199-92-2 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Cyclopropyl-3-methyl-1h-pyrazole-5-carboxylic acid (CAS 1254199-92-2), a certified reference material (molecular formula C8H10N2O2, MW 166.18 g/mol) for analytical method development and quality control.
1-Cyclopropyl-3-methyl-1h-pyrazole-5-carboxylic acid (C8H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-Cyclopropyl-3-methyl-1h-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- Methyl 3-cyclopropyl-1h-pyrazole-5-carboxylate (CAS 1036733-11-5)
- 5-Cyclopropyl-1-methyl-1h-pyrazole-4-carboxylic acid (CAS 1092394-30-3)
- 5-Cyclopropyl-N-methylisoxazole-4-carboxamide (CAS 124845-01-8)
- Methyl 2-cyclopropyl-1h-imidazole-4-carboxylate (CAS 1250136-57-2)
- methyl 1-cyclopropyl-1H-imidazole-4-carboxylate (CAS 1260655-08-0)
- 3-Cyclopropyl-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1287752-79-7)
- N-Cyclopropyl-5-methylisoxazole-3-carboxamide (CAS 135401-17-1)
- 2-(1-Cyclopropyl-1H-imidazol-5-yl)acetic acid (CAS 1368104-51-1)
Recommended Standards
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- 4-Propylpyrimidine-5-carboxylic acid (CAS 1250812-18-0)
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- 8-Nitro-1,2,3,4,5,9b-hexahydrobenzo[c]thieno[2,1-e]isothiazole 4-oxide (CAS 2169311-00-4)
- 3-Phenyldibenzothiophene (CAS 98251-30-0)
- 3-(Diethoxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1333319-77-9)
- 3-(2-Methoxyethyl)-4-methyl-1h-pyrazol-5-amine (CAS 1187766-96-6)
- N,N-Diisopropyl-5-phenylphosphinin-3-amine (CAS 89337-58-6)
- 2(1H)-Pyridinone, 1-butyl-4-(4-phenyl-1-piperidinyl)- (CAS 1127499-59-5)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
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