3,3′-(1,2-Ethynediyl)bis[5-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)pyridine] CAS 1254929-22-0
| CAS No. | 1254929-22-0 |
| Molecular Formula | C22H22N4O2 |
| Molecular Weight | 374.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3′-(1,2-Ethynediyl)bis[5-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)pyridine] (CAS 1254929-22-0), molecular formula C22H22N4O2 and molecular weight 374.44 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 3,3′-(1,2-Ethynediyl)bis[5-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)pyridine] is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22N4O2 |
| Molecular Weight | 374.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Ethynediyl Standards
Recommended Standards
- 5-((4-((1-Methylpiperidin-4-yl)amino)-5-(1H-pyrrol-1-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CAS 1137476-66-4)
- N,1-bis(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine (CAS 1415559-83-9)
- Glasdegib (CAS 1095173-27-5)
- N-(3-Cyanophenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574626-63-3)
- 3-Bromo-5-(3,3-difluoropyrrolidin-1-ylmethyl)-pyridine (CAS 1428065-38-6)
- 4-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)butanoic acid (CAS 1421602-08-5)
- 2-((4-Chlorophenyl)thio)-1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethan-1-one (CAS 478029-63-9)
- 3-Chloro-N-(4-chloro-2-((5-chloropyridin-2-yl)carbamoyl)-6-methoxyphenyl)-4-((2-(methylamino)-1H-imidazol-1-yl)methyl)thiophene-2-carboxamide 2,2,2-trifluoroacetate (CAS 229340-73-2)
- 3-Chloro-4-(pyridin-4-yloxy)benzoic acid hydrochloride (CAS 1306604-54-5)
- 3-(Bromomethyl)-5-(trifluoromethyl)pyridine hydrobromide (CAS 1384972-85-3)
- 4-(Acetylamino)-3-bromobenzenesulfonyl Chloride (CAS 88963-75-1)
- 5-Bromo-2-chloro-4-ethyl-3-nitropyridine (CAS 1638759-95-1)
- 1-Chloro-4-(isopropylsulfonyl)benzene (CAS 7205-83-6)
- Peptide Impurity 34 (CAS 21282-09-7)
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