1-(2-Carboxyphenyl)-5-oxopyrrolidine-3-carboxylic acid CAS 1255147-76-2
| CAS No. | 1255147-76-2 |
| Molecular Formula | C12H11NO5 |
| Molecular Weight | 249.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Carboxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1255147-76-2), molecular formula C12H11NO5 and molecular weight 249.22 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2-Carboxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (C12H11NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO5 |
| Molecular Weight | 249.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Carboxyphenyl Standards
- 1-(3-Carboxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 43094-96-8)
- 1-(4-Carboxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 40306-01-2)
- 1-(4-Carboxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 18502-39-1)
- 2,2'-((3-Carboxyphenyl)azanediyl)diacetic acid (CAS 93534-69-1)
- 2-(2-Carboxyphenyl)thiazolidine-4-carboxylic acid (CAS 82625-89-6)
- (3-carboxyphenyl)boronic acid, pinacol ester 269409-73-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-benzoic acid 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid 3-Carboxyphenylboronic acid pinacol ester 3-carboxyphenylboronic acid, pinacol ester (CAS 269409-73-6)
- 4-(4-Carboxyphenyl)-2-methoxyphenol (CAS 189161-82-8)
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Recommended Standards
- (Z)-4-((4-(methoxycarbonyl)phenyl)amino)-4-oxobut-2-enoic acid (CAS 125407-30-9)
- 1-(5-Methoxy-2-nitro-4-(prop-2-yn-1-yloxy)phenyl)ethan-1-one (CAS 1255792-04-1)
- (4-methoxy-3-nitrophenyl)methanesulfonyl fluoride (CAS 1251924-42-1)
- (S)-n-(2,5-Dioxotetrahydrofuran-3-yl)-2-phenoxyacetamide (CAS 1257855-08-5)
- 6-[3-(Trifluoromethyl)phenyl]pyrimidin-4-ol (CAS 400087-19-6)
- 7-Fluoro-6-(hydroxymethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 443955-37-1)
- 2-(4-(Difluoromethoxy)phenyl)-2-methylpropan-1-ol (CAS 80854-17-7)
- 6-Methyl-5,6,7,8-tetrahydropyrido[3,4-b]pyrazin-2-amine (CAS 777807-25-7)
- Dibenzo[b,e][1,4]dioxine-2,3,7,8-tetraamine (CAS 34294-67-2)
- tert-butyl 2-(3-hydroxy-2-oxoazepan-1-yl)acetate (CAS 2060042-67-1)
- Ethyl (tetrahydro-2h-pyran-4-yl)glycinate (CAS 1153226-50-6)
- 3-Amino-4-methylpicolinonitrile (CAS 183428-92-4)
- 2'-Isopropylspiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2973-07-1)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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