1-(Tert-butyl) 2-methyl 4,4-difluoropiperidine-1,2-dicarboxylate CAS 1255666-28-4
| CAS No. | 1255666-28-4 |
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-(Tert-butyl) 2-methyl 4,4-difluoropiperidine-1,2-dicarboxylate (C12H19F2NO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 279.28 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-(Tert-butyl) 2-methyl 4,4-difluoropiperidine-1,2-dicarboxylate (CAS 1255666-28-4), a certified reference material (molecular formula C12H19F2NO4, MW 279.28 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 1-tert-Butyl 2-methyl 5,5-difluoropiperidine-1,2-dicarboxylate (CAS 1255663-86-5)
- Methyl 1-Boc-5,5-difluoropiperidine-3-carboxylate (CAS 1255667-06-1)
- N-((1,3,5-Triazin-2-yl)carbamoyl)benzenesulfonamide (CAS 122252-37-3)
- 2-(1-(Boc)Piperidin-4-yl)-2,2-difluoroacetic acid (CAS 1258638-62-8)
- tert-Butyl 4-(((3-chloroquinoxalin-2-yl)amino)methyl)piperidine-1-carboxylate (CAS 939986-05-7)
- 6-Chloro-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride (CAS 1260638-90-1)
- (R)-2-((tert-butyldimethylsilyl)oxy)propan-1-ol (CAS 265309-82-8)
- 3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane 4-methylbenzenesulfonate (CAS 423165-08-6)
- 6-(Ethylthio)-4-hydroxyheptan-2-one (CAS 76938-92-6)
- L-Leucine-2-d1 (CAS 89836-93-1)
- (5S)-1,4-oxazepane-5-carboxylic acid (CAS 2165429-68-3)
- 2-(4-Methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 1311186-67-0)
- N-(5-Amino-2-fluorophenyl)-2-(4-methoxyphenyl)-acetamide (CAS 1016725-04-4)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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