(3R,4S)-1-(tert-butoxycarbonyl)-4-(3-ethylphenyl)pyrrolidine-3-carboxylic acid CAS 1255933-99-3
| CAS No. | 1255933-99-3 |
| Molecular Formula | C18H25NO4 |
| Molecular Weight | 319.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(3R,4S)-1-(tert-butoxycarbonyl)-4-(3-ethylphenyl)pyrrolidine-3-carboxylic acid (CAS 1255933-99-3), molecular formula C18H25NO4 and molecular weight 319.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3R,4S)-1-(tert-butoxycarbonyl)-4-(3-ethylphenyl)pyrrolidine-3-carboxylic acid (C18H25NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), (3R,4S)-1-(tert-butoxycarbonyl)-4-(3-ethylphenyl)pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H25NO4 |
| Molecular Weight | 319.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl 3-((tert-butoxycarbonyl)amino)-2,2-dimethyl-2,3-dihydro-1H-indene-5-carboxylate (CAS 1246508-44-0)
- (S)-1-(Morpholino(phenyl)methyl)naphthalen-2-ol (CAS 1260596-62-0)
- Methyl 3-((tert-butoxycarbonyl)amino)-1,1-dimethyl-2,3-dihydro-1H-indene-5-carboxylate (CAS 1246505-85-0)
- (2R,5S)-5-Benzyl-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid (CAS 1260603-65-3)
- Ethyl N-(tert-butoxycarbonyl)-3-iodophenylalaninate (CAS 1922842-97-4)
- 2-Amino-6-(hydroxymethyl)-4-(2-nitrophenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 625376-11-6)
- (S)-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 68000-22-6)
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