2-Fluoro-6-hydroxyphenylboronic Acid CAS 1256345-60-4
| CAS No. | 1256345-60-4 |
| Molecular Formula | C6H6BFO3 |
| Molecular Weight | 155.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Fluoro-6-hydroxyphenylboronic Acid (CAS 1256345-60-4), molecular formula C6H6BFO3 and molecular weight 155.92 g/mol, is a CATO reference standard with documented purity and traceability.
2-Fluoro-6-hydroxyphenylboronic Acid (C6H6BFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6BFO3 |
| Molecular Weight | 155.92 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-5-hydroxyphenylboronic Acid (CAS 1150114-52-5)
- 3-Fluoro-4-hydroxyphenylboronic Acid (CAS 182344-14-5)
- (3-fluoro-2-hydroxy-phenyl)boronic acid (CAS 259209-24-0)
- 2-Fluoro-3-hydroxyphenylboronic Acid (CAS 855230-60-3)
- 3-Fluoro-5-hydroxyphenylboronic Acid (CAS 871329-82-7)
- 4-Fluoro-2-hydroxyphenylboronic Acid (CAS 850568-00-2)
- 5-Fluoro-2-hydroxyphenylboronic Acid (CAS 259209-20-6)
- 5-Fluoro-2-methyl-3-nitropyridine (CAS 1162674-71-6)
Recommended Standards
- (6-Amino-2-fluoropyridin-3-yl)boronic acid (CAS 1225228-43-2)
- (2-amino-3-fluoropyridin-4-yl)boronic acid (CAS 1310384-05-4)
- (2-Amino-6-fluoropyridin-4-yl)boronic acid (CAS 1214879-87-4)
- (6-Amino-5-fluoropyridin-3-yl)boronic acid (CAS 1310404-43-3)
- (5-Chlorothiazol-2-yl)methanamine (CAS 1187933-28-3)
- (1S,2R,3R,4S)-cyclohex-5-ene-1,2,3,4-tetraol (CAS 138258-55-6)
- 2-(Difluoromethyl)-4,6-dimethoxy-3-methylpyridine (CAS 1804452-80-9)
- 6-Isopropylquinoline (CAS 135-79-5)
- 2-(4,6-Diphenyl-1,2,3-triazin-5-yl)-1-phenylethanone (CAS 170750-50-2)
- 3-(Perfluoro-7-methyloctyl)-2-hydroxypropylmethacrylate (CAS 88752-37-8)
- 4-Ethylpyrazolidine-3,5-dione (CAS 23876-80-4)
- 4-(Cyclohexylmethyl)-2-(methylthio)phenol (CAS 1243287-62-8)
- N1-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine (CAS 1089330-39-1)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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