(2-(Benzyloxy)-3-fluorophenyl)boronic acid CAS 1256355-53-9
| CAS No. | 1256355-53-9 |
| Molecular Formula | C13H12BFO3 |
| Molecular Weight | 246.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2-(Benzyloxy)-3-fluorophenyl)boronic acid (CAS 1256355-53-9), molecular formula C13H12BFO3 and molecular weight 246.04 g/mol, is a CATO reference standard with documented purity and traceability.
(2-(Benzyloxy)-3-fluorophenyl)boronic acid (C13H12BFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12BFO3 |
| Molecular Weight | 246.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Benzyloxy Standards
- (2-(Benzyloxy)-6-fluorophenyl)boronic acid (CAS 1217500-53-2)
- (5-(Benzyloxy)-2-fluorophenyl)boronic acid (CAS 1217500-68-9)
- 4-Benzyloxy-3-fluorophenylboronic acid (CAS 133057-83-7)
- 4-(Benzyloxy)-2-fluorophenylboronic Acid (CAS 166744-78-1)
- (2-(Benzyloxy)-4-fluorophenyl)boronic acid (CAS 848779-87-3)
- (2-(Benzyloxy)-5-fluorophenyl)boronic acid (CAS 779331-47-4)
- 3-Benzyloxy-4-fluorophenylboronic acid (CAS 957034-74-1)
- 3-Benzyloxy-5-fluorophenylboronic acid (CAS 850589-56-9)
Recommended Standards
- Arsenic(III) sulfide (99.9%-As) (CAS 1303-33-9)
- (3-((4-Fluorobenzyl)oxy)phenyl)boronic acid (CAS 1072952-03-4)
- [2-(4-fluorophenoxymethyl)phenyl]boronic acid (CAS 1334325-11-9)
- (4-((3-Fluorobenzyl)oxy)phenyl)boronic acid (CAS 1072951-98-4)
- (R)-3-amino-3-(4-isopropylphenyl)propanoic acid (CAS 1196690-98-8)
- Ethyl 4-bromo-5-chloro-2-nitrobenzoate (CAS 1845689-93-1)
- 1-(2,4-Dichloro-5-methoxyphenyl)-5-methyl-N-(4-phenoxyphenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 339015-16-6)
- 2-(5-Amino-1,3,4-thiadiazol-2-yl)-1-(piperidin-1-yl)ethan-1-one (CAS 797027-61-3)
- 6-Bromo-5-chloropyridin-2-amine (CAS 1004294-58-9)
- tert-Butyl N-(4,4,4-trifluoro-1-oxobutan-2-yl)carbamate (CAS 1056467-83-4)
- cis-1-Amino-indan-2-carboxylic acid ethyl ester hydrochloride (CAS 327178-34-7)
- 799812-63-8 (2S,3R,4E)-2-Azaniumyl-3-hydroxy-18-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octadec-4-en-1-yl hydrogen phosphate DTXSID80677052 (CAS 799812-63-8)
- 4-Chloro-3-(trifluoromethyl)benzenesulfonic acid (CAS 1644-79-7)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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