(5-Fluoro-2-((3-fluorobenzyl)oxy)phenyl)boronic acid CAS 1256358-53-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1256358-53-8
Molecular FormulaC13H11BF2O3
Molecular Weight264.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-Fluoro-2-((3-fluorobenzyl)oxy)phenyl)boronic acid CAS 1256358-53-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Fluoro-2-((3-fluorobenzyl)oxy)phenyl)boronic acid.

(5-Fluoro-2-((3-fluorobenzyl)oxy)phenyl)boronic acid (CAS 1256358-53-8) is a high-purity analytical reference standard with the molecular formula C13H11BF2O3 and a molecular weight of 264.03 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (5-Fluoro-2-((3-fluorobenzyl)oxy)phenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 264.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H11BF2O3
Molecular Weight264.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing

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