tert-Butyl 4-(2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate CAS 1256360-53-8
| CAS No. | 1256360-53-8 |
| Molecular Formula | C22H34BFN2O4 |
| Molecular Weight | 420.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl 4-(2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate (C22H34BFN2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
tert-Butyl 4-(2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate (CAS 1256360-53-8), molecular formula C22H34BFN2O4 and molecular weight 420.33 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl 4-(2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H34BFN2O4 |
| Molecular Weight | 420.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
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- Ethyl 5-(trifluoroacetyl)-3-(trifluoromethyl)naphtho[1,2-b]thiophene-2-carboxylate (CAS 140666-92-8)
- Bromperidol (CAS 10457-90-6)
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- (S)-2-Cyclopropyl-1-(3-fluoro-4-methylphenyl)ethanamine (CAS 321840-50-0)
- (R)-tert-Butyl 3-(2-fluorobenzylamino)piperidine-1-carboxylate (CAS 1286208-54-5)
- Quinoline-7,8-diamine (CAS 78105-42-7)
- 2-(4-((2-Methylbutyl)amino)phenyl)acetonitrile (CAS 1157648-79-7)
- 3-(3-Hydroxy-1-oxo-1H-inden-2-yl)-4,6-dioxo-5-(3-(trifluoromethyl)phenyl)-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid (CAS 321521-98-6)
- Rebamipide Impurity 63 (CAS CATO-C4X-152363)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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