2,2,2-Trifluoro-1-(4-fluoro-3,5-dimethylphenyl)ethanone CAS 1256467-41-0
| CAS No. | 1256467-41-0 |
| Molecular Formula | C10H8F4O |
| Molecular Weight | 220.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,2,2-Trifluoro-1-(4-fluoro-3,5-dimethylphenyl)ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2,2,2-Trifluoro-1-(4-fluoro-3,5-dimethylphenyl)ethanone (CAS 1256467-41-0) is a high-purity analytical reference standard with the molecular formula C10H8F4O and a molecular weight of 220.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2,2-Trifluoro-1-(4-fluoro-3,5-dimethylphenyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F4O |
| Molecular Weight | 220.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 4,4,4-Trifluoro-1-(1-methyl-1h-pyrazol-4-yl)butane-1,3-dione (CAS 1005592-50-6)
- 4,4,4-Trifluoro-1-(1-methyl-1h-pyrazol-3-yl)butane-1,3-dione (CAS 1006319-27-2)
- Ethyl 2,3,5-trifluoro-4-hydroxybenzoate (CAS 1214351-42-4)
- 2,2,2-Trifluoro-1-(3-nitrophenyl)ethan-1-amine (CAS 1248504-66-6)
- 2,2,2-Trifluoro-1-(4-nitrophenyl)ethanamine (CAS 1270543-98-0)
- Ethyl 2,4,5-trifluoro-3-hydroxybenzoate (CAS 128426-84-6)
- (S)-4-(2,2,2-Trifluoro-1-hydroxyethyl)benzoic acid (CAS 130534-97-3)
- (R)-4-(2,2,2-Trifluoro-1-hydroxyethyl)benzoic acid (CAS 150821-42-4)
Recommended Standards
- 2-(Pentafluoro-lambda6-sulfanyl)phenol (CAS 1126968-75-9)
- 1-(4-Fluoro-2-(trifluoromethyl)phenyl)propan-2-one (CAS 1305323-89-0)
- Travoprost Impurity 6 (CAS 349-82-6)
- 1-(5-Fluoro-2-(trifluoromethyl)phenyl)propan-2-one (CAS 1305324-01-9)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chloro-2-fluorophenyl)methanone (CAS 898758-25-3)
- (2Z)-2-(4-tert-Butylbenzylidene)-6-hydroxy-1-benzofuran-3(2H)-one (CAS 620545-95-1)
- 3-Bromo-4,5-dihydroisoxazole (CAS 288370-87-6)
- 6-(tert-Butoxy)-5-cyclopropoxypicolinonitrile (CAS 1243411-05-3)
- 2,4-Dimethyl-3-fluorobenzyl alcohol (CAS 26583-82-4)
- 3-Bromo-2-(4-bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-79-3)
- N-cyclopentyl-5-methylisoxazole-3-carboxamide (CAS 135401-66-0)
- 2-(3-(4-Hydroxyphenyl)-4-(4-methoxyphenyl)isoxazol-5-yl)acetic acid (CAS 112453-43-7)
- 1-(Oxan-3-yl)methanamine carbonic acid (CAS 118836-05-8)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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