1-[7-Hydroxy-2-(trifluoromethyl)[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl]ethanone CAS 1256627-91-4
| CAS No. | 1256627-91-4 |
| Molecular Formula | C8H5F3N4O2 |
| Molecular Weight | 246.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[7-Hydroxy-2-(trifluoromethyl)[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl]ethanone (CAS 1256627-91-4), molecular formula C8H5F3N4O2 and molecular weight 246.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-[7-Hydroxy-2-(trifluoromethyl)[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl]ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[7-Hydroxy-2-(trifluoromethyl)[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl]ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N4O2 |
| Molecular Weight | 246.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Hydroxy Standards
- 4-Hydroxy-6-(trifluoromethoxy)-2H-chromen-2-one (CAS 1499667-28-5)
- 4-Hydroxy Clonidine (CAS 57101-48-1)
- 4-Hydroxy-6-oxo-1-(o-tolyl)-1,6-dihydropyridazine-3-carboxylic acid (CAS 1018251-59-6)
- 4-Hydroxy-6-oxo-1-(m-tolyl)-1,6-dihydropyridazine-3-carboxylic acid (CAS 1018276-57-7)
- Methyl 4-hydroxy-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 121582-53-4)
- 1-Benzyl-6-hydroxy-2-oxo-1,2-dihydropyrimidine-4-carboxylic acid (CAS 338774-89-3)
- 2-Hydroxy-6-(4-methoxyphenyl)pyrimidine-4-carboxylic acid (CAS 55558-82-2)
- 4-((5-Hydroxy-6-methyl-1,2,4-triazin-3-yl)amino)benzoic acid (CAS 459180-96-2)
Recommended Standards
- 4-Bromo-1-(2-methylpentyl)-1h-pyrazol-3-amine (CAS 1249867-00-2)
- 7-Methyl-3-nitro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 1281984-46-0)
- 4-Bromo-1-(3,3-dimethylbutyl)-1h-pyrazol-3-amine (CAS 1247438-03-4)
- 4-Bromo-1-hexyl-1h-pyrazol-3-amine (CAS 1282752-36-6)
- Azido-PEG11-CH2COOH (CAS 2567584-97-6)
- (R)-2-Methoxy-5-(piperidin-2-yl)pyridine (CAS 1134621-24-1)
- 2-(3-Hydroxy-4-nitrobenzylidene)malononitrile (CAS 118409-62-4)
- N-(6-Fluoro-1,3-benzothiazol-2-yl)-N,N-dimethylpropane-1,3-diamine (CAS 1105195-09-2)
- 5-Chloro-4-iodo-2-methylpyridine (CAS 1245134-39-7)
- 2-vinyloxyethylcyclohexane (CAS 103983-46-6)
- 1-Isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 4014-61-3)
- (S)-5-Ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxybenzamide (CAS 134024-44-5)
- 5-((2,4-Dichlorophenoxy)methyl)-3-phenylisoxazole (CAS 672951-45-0)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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