4-(Difluoromethyl)picolinic acid CAS 1256804-49-5
| CAS No. | 1256804-49-5 |
| Molecular Formula | C7H5F2NO2 |
| Molecular Weight | 173.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Difluoromethyl)picolinic acid (CAS 1256804-49-5) is a high-purity analytical reference standard with the molecular formula C7H5F2NO2 and a molecular weight of 173.12 g/mol.
Structurally, 4-(Difluoromethyl)picolinic acid (C7H5F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 173.12 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-(Difluoromethyl)picolinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F2NO2 |
| Molecular Weight | 173.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 3-(Difluoromethyl)pyridine-4-carboxylic acid (CAS 1211541-32-0)
- 4-(Difluoromethyl)nicotinic acid (CAS 1211590-78-1)
- 3-(Difluoromethyl)pyridine-2-carboxylic acid (CAS 1256794-75-8)
- 2-(Difluoromethyl)pyridine-3-carboxylic acid (CAS 1256809-21-8)
- 5-(Difluoromethyl)nicotinic acid (CAS 1256817-25-0)
- 2-(Difluoromethyl)isonicotinic acid, 97% (CAS 1256818-14-0)
- 6-(Difluoromethyl)-2-pyridinecarboxylic Acid (CAS 1256824-41-5)
- 1-(Difluoromethyl)-2-oxo-1,2-dihydropyridine-3-carbaldehyde (CAS 1263178-10-4)
Recommended Standards
- 3,5-Difluoropicolinohydrazide (CAS 1254073-43-2)
- 2,6-Difluoro-N-hydroxybenzamide (CAS 125309-34-4)
- 3-(methoxycarbonyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1251924-30-7)
- 2,2-Difluoro-2-(pyridin-3-yl)acetic acid (CAS 1247461-08-0)
- 4,6-Dichloro-2-methylquinazoline (CAS 338739-44-9)
- (4-Hydroxyphenyl)(4-methylpiperazin-1-yl)methanone (CAS 85858-94-2)
- Diethyl 2-(dimethylamino)malonate (CAS 89222-12-8)
- 170874-47-2 adenosine, 4'-C-fluoro- (CAS 170874-47-2)
- 4-(Cyclopropylamino)piperidine-4-carboxamide dihydrochloride (CAS 1172804-60-2)
- Benzyl 4-aminopyrimidine-5-carboxylate (CAS 1706446-70-9)
- Grazoprevir (CAS 1350514-68-9)
- Methyl 2,6-bis(trifluoromethyl)nicotinate (CAS 137144-34-4)
- Tert-butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxo-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)carbamate (CAS 1844874-05-0)
- [D-Ser8]-Semaglutide A (CAS CATO-C4X-2226116)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com